The Bible begins with a profound statement: “In the beginning God created the heaven and the earth.” (Ge 1:1) It’s a scientific statement, yet it’s also obviously a metaphysical and a spiritual one, a link between spirituality and science. How so?
The 1st and 2nd Laws of Thermodynamics, basic rules which no scientific observation has ever violated, tell us:  matter and energy can’t be created, or come into existence from nothing, naturally (The Law of Conservation of Energy explicitly states this.); and  the universe came into existence – it’s not infinitely old; it had a beginning, before which there was nothing (The Law of Increasing Entropy implies this by contradiction: an infinitely old universe would be at steady state with maximum entropy, and our universe is not so).
Putting these two facts together implies that a supernatural event, a miracle, must occur for anything at all to exist – the material universe had to be created by a deity. In other words, the basic, time-tested laws of physics prove that God exists. To deny this is to deny everything we’ve ever discovered about the universe through science.
And, by definition, a miracle is a spiritual thing, an act of deity which reveals the existence, nature and character of the divine. The earth and the heavens are such a miracle, declaring the glory of God (Ps 19:1) to all Mankind. (Ro 1:20)
So why are there atheists and agnostics? Those I’ve encountered say science has discredited and replaced spirituality, that it can explain anything. Yet it seems to me that skeptics must ignore science in order to persist in disbelief. They appear to be living exactly like the religious simpletons they disdain, blindly ignoring the One they’re desperately hoping doesn’t exist.
If we don’t obey the truth we already know we deceive ourselves. (Ja 1:22) We’re each accountable for how we respond to evidence; a persistent unwillingness to acknowledge God and seek after Him (Ac 17:27) reveals an enmity towards Him that’s entirely unjustified. (Ro 8:6) It would make anyone with any self-respect angry to be treated like this — of course it makes God angry. (Ro 1:18-19) Why wouldn’t it?